03-28-2020, 01:32 AM
I'd read that there are young people with the most severe form of the disease, and it presents identically to the severe form in the elderly.
While eating lunch today, it occurred to me that disease severity might depend on route of infection, not just age, general immune competence, or genetic factors: If it gets in some way other than the lungs, the host may have time to build partial immunity by the time it reaches the lungs, and have the mild course of the disease. In which case, the virus could serve as its own vaccine: Purposefully inoculate people via the safest route, before they accidentally breathe it in.
Found an article about severity vs route of infection; haven't had time to read all of it yet.
"Association of COVID-19 Disease Severity with Transmission Routes and Suggested Changes to Community Guidelines"
https://www.preprints.org/manuscript/202...1/download
While eating lunch today, it occurred to me that disease severity might depend on route of infection, not just age, general immune competence, or genetic factors: If it gets in some way other than the lungs, the host may have time to build partial immunity by the time it reaches the lungs, and have the mild course of the disease. In which case, the virus could serve as its own vaccine: Purposefully inoculate people via the safest route, before they accidentally breathe it in.
Found an article about severity vs route of infection; haven't had time to read all of it yet.
"Association of COVID-19 Disease Severity with Transmission Routes and Suggested Changes to Community Guidelines"
https://www.preprints.org/manuscript/202...1/download
